大型仪器与实验中心

姓名：刘志广

职称：高级实验师

所在专业：环境科学

个人简介：博士，高级实验师，硕士研究生导师。主要研究方向：电分析化学、纳米材料修饰电极、环境污染物检测。

招生方向：环境污染物分析检测

联系方式：E-mail:Liuzg@sxu.edu.cn

教育背景：

2002年，理学学士，山西大学生物化学专业

2008年，理学硕士，山西大学生物化学与分子生物学专业

2016年，工学博士，山西大学环境科学专业

工作经历：

2013.08~2019.01，实验师，山西大学环境科学研究所；

2019.01~今，高级实验师，山西大学环境科学研究所；

2019.09~2020.09，访问学者，加拿大不列颠哥伦比亚大学（UBC）。

主要科研成果：

针对目前水中环境污染物检测的关键科学问题，利用电化学分析方法发展新的检测技术。近年来，设计合成了一系列新型的功能化石墨烯纳米复合材料，构建电化学传感器，实现了对环境污染物（酚类和重金属离子等）、疾病标志物（癌胚抗原、葡萄糖等）和药物（黄芩、异槲皮苷、芦丁）等的高灵敏检测，为水中的污染物分析检测和恶性肿瘤等重大疾病的早期诊断提供理论基础和新技术。

主持山西省回国留学人员科研资助项目1项，参与国家自然科学基金面上项目2项。在《Biosensors and Bioelectronics》、《Talanta》、《Journal of the Electrochemical Society》、《Analytical Chemisty》、《Journal of Electroanalytical Chemistry》及《Electroanalysis》等SCI期刊上发表论文40余篇，其中TOP1区5篇，他引200余次。授权国家发明和实用新型专利10项；参编《纳米电化学与环境检测》国家级统编教材1部；研究成果获山西省科学技术奖（自然科学类）一等奖（排名第2）1项。

主要学术论文：

(1) Zhiguang Liu, Ai Zhang, Yujing Guo*, Chuan Dong*, Electrochemical Sensor for Ultrasensitive Determination of Isoquercitrin and Baicalin Based on DM-β-Cyclodextrin Functionalized Graphene Nanosheets, Biosensors and Bioelectronics, 2014，58: 242-248. (SCI 1区，TOP，IF：5.830)

(2) Zhiguang Liu， Qiong Xue, Yujing Guo*, Sensitive electrochemical detection of rutin and isoquercitrin based on SH-beta-cyclodextrin functionalized graphene-palladium nanoparticles, Biosensors and Bioelectronics, 2017, 89：444-452. (SCI 1区, TOP, IF：8.173)

(3) Zhiguang Liu, Yujing Guo*, Chuan Dong*, A high performance nonenzymatic electrochemical glucose sensor based on polyvinylpyrrolidone-graphene nanosheets-nickel nanoparticles-chitosan nanocomposite, Talanta, 2015，137: 87-93. (SCI 1区, TOP, IF：6.1)

(4) Zhiguang Liu, Yuxuan Wang, Yujing Guo*, Chuan Dong*, Label-free Electrochemical Aptasensor for Carcino-embryonic Antigen Based on Ternary Nanocomposite of Gold Nanoparticles, Hemin and Graphene, Electroanalysis, 2016, 28(5)：1023-1028. (SCI 3区, IF：2.851)

(5) Zhiguang Liu, Yujing Guo*, Sensitive determination of trace 4-nitrophenol in water based on thio-β-cyclodextrin functionalized graphene/copper nanospheres, Journal of Electroanalytical Chemistry, 2018，825:57-64. (SCI 3区，IF：3.012)

(6) Qiong Xue, Zhiguang Liu, Yujing Guo*, Shaojun Guo. Cyclodextrin functionalized graphene–gold nanoparticle hybrids with strong supramolecular capability for electrochemical thrombin aptasensor. Biosensors and Bioelectronics, 2015，68: 429–436. (SCI 1区，TOP，IF：5.830)

(7) Guojuan Zhang, Zhiguang Liu, Lifang Fan, Yujie Han, Yujing Guo*, A novel dual signal and label-free electrochemical aptasensor for mucin 1 based on hemin/graphene@PdPtNPs, Biosensors and Bioelectronics, 2021，173: 112785. (SCI 1区，TOP，IF：9.316)

(8) Tingting Li, Zhiguang Liu, Li Wang*, Yujing Guo*, Gold nanoparticles /Orange II functionalized graphene nanohybrid based electrochemical aptasensor for label-free determination of insulin, RSC Advances, 2016, 6(36): 30732~30738. (SCI 2区)

(9) Guojuan Zhang, Zhiguang Liu, Lifang Fan， Yujing Guo*， Electrochemical prostate specific antigen aptasensor based on hemin functionalized graphene-conjugated palladium nanocomposites， Microchimica Acta，2018，185: 159. (SCI 2区)

(10) Tingxuan Wu, Tingting Li, Zhiguang Liu, Yujing Guo*, Chuan Dong*, Electrochemical sensor for sensitive detection of triclosan based on graphene/palladium nanoparticles hybrids, Talanta, 2017, 164: 556~562. (SCI 2区)

(11) Tingxuan Wu, Zhiguang liu, Yujing Guo*, Chuan Dong*. Electrochemical sensor for facile detection of trace luteolin based on thio-β-cyclodextrin functionalized graphene/gold nanoparticles hybrids. Journal of Electroanalytical Chemistry, 2015，759:137-143. (SCI 3区，IF：2.757)

(12) Guojuan Zhang, Zhiguang Liu, Li Wang, Yujing Guo*， Electrochemical Aptasensor for Myoglobin-Specific Recognition Based on Porphyrin Functionalized Graphene-Conjugated Gold Nanocomposites，Sensors，2016，16:1803. (SCI 3区)

(13) Jinfeng Zou, Zhiguang Liu, Yujing Guo*， Chuan Dong， Electrochemical sensor for the facile detection of trace amounts of bisphenol A based on cyclodextrin-functionalized graphene/platinum nanoparticles，Analytical Methods, 2017, 9:134-140. (SCI 3区)

(14) Fenglin Zhang, Zhiguang Liu, Yujie Han, Lifang Fan, Yujing Guo*，A facile electrochemical aptasensing platform based on a polydopamine@graphene composite for protein detection, Analytical methods, 2018, 10: 5547-5553. (SCI 3区)

(15) Congli Wang, Tingting Li, Zhiguang Liu, Yujing Guo, Chenzhong Li, Chuan Dong, Shaomin Shuang *, An ultra-sensitive sensor based on beta-cyclodextrin modified magnetic graphene oxide for detection of tryptophan, Journal of Electroanalytical Chemistry, 2016, 781: 363~370. (SCI 3区)

(16) Faqiang Zhong, Zhiguang Liu, Yujie Han, Yujing Guo*, Electrochemical Sensor for Sensitive Determination of Capsaicin Using Pd Decorated Reduced Graphene Oxide, Electroanalysis, 2019, 31：1182-1188. (SCI 3区)

(17) Yujie Han, Xujie Su, Lifang Fan, Zhiguang Liu, Yujing Guo*, Electrochemical aptasensor for sensitive detection of Cardiac troponin I based on CuNWs/MoS2/rGO nanocomposite, Microchemical Journal, 2021, 169: 106598. (SCI 3区)

(18) Xujie Su, Yujie Han, Zhiguang Liu, Lifang Fan, Yujing Guo*, One-pot synthesized AuNPs/MoS2/rGO nanocomposite as sensitive electrochemical aptasensing platform for nucleolin detection, Journal of Electroanalytical Chemistry, 2020, 859: 113868. (SCI 3区)

(19) Miaomiao Li, Xiuying Peng, Yujie Han, Lifang Fan, Zhiguang Liu, Yujing Guo*, Ti3C2 MXenes with intrinsic peroxidase-like activity for label-free and colorimetric sensing of proteins, Microchemical Journal, 2021, 166: 106238. (SCI 3区)

(20) 韩丽君，刘志广，郭玉晶*，PVP功能化石墨烯高效吸附废水中大分子染料.《水处理技术》，2019，45(3):48-54.（二级学科主学报）

主要授权专利：

(1) 刘志广，董川，双少敏，郭玉晶，韩玉洁，一种可反复标注循环使用的教科书，专利号：ZL 201920658796.8

(2) 刘志广，董川，郭玉晶，一种用于擦除水擦墨水字迹的板擦，专利号：ZL201921296800.7

(3) 刘志广，郭玉晶，薛琼，双少敏，董川，一种电极表面修饰材料及其制备方法和应用，专利号：ZL 201410543059.5

(4) 刘志广，郭玉晶，董川，一种电极表面修饰材料及其制备方法和应用，专利号：ZL 201710804391.6

(5) 李明璐，刘志广，梁帆，宋胜梅，董川，双少敏，一种米黄色吸磁性涂料及其制备方法，专利号：ZL 201810882580.X

主持和参与的主要项目：

(1) 纳米酶的可控电化学合成及其在重金属离子传感中的应用，山西省回国留学人员科研资助项目，项目编号：2021-013。（主持）

(2) 石墨烯/过渡金属硫化物纳米复合材料电化学适配体传感器的构建及其在肿瘤标记物检测中的应用，国家自然科学基金，项目编号：21775095。（参与）

(3) 基于石墨烯杂化材料-核酸适配体的新型电化学生物传感器的设计和研究，国家自然科学基金，项目编号：21275093。（参与）